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Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome

The myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis, dysplasia, and transformation to acute myeloid leukemia (AML). Although it has been suggested that additional mutations lead to progression of MDS to AML, the causative agent(s) for such mutations remains unclear. Ox...

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Détails bibliographiques
Auteurs principaux: Chung, Yang Jo, Robert, Carine, Gough, Sheryl M., Rassool, Feyruz V., Aplan, Peter D.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872269/
https://ncbi.nlm.nih.gov/pubmed/23958061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.07.008
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