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Oxidative stress leads to increased mutation frequency in a murine model of myelodysplastic syndrome

The myelodysplastic syndromes (MDS) are characterized by ineffective hematopoiesis, dysplasia, and transformation to acute myeloid leukemia (AML). Although it has been suggested that additional mutations lead to progression of MDS to AML, the causative agent(s) for such mutations remains unclear. Ox...

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Detalhes bibliográficos
Main Authors: Chung, Yang Jo, Robert, Carine, Gough, Sheryl M., Rassool, Feyruz V., Aplan, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3872269/
https://ncbi.nlm.nih.gov/pubmed/23958061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.07.008
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