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NUP98-HOX translocations lead to myelodysplastic syndrome in mice and men

The myelodysplastic syndromes (MDS) are a group of clonal hematopoietic stem cell disorders characterized by ineffective hematopoiesis, peripheral blood cytopenias, dysplasia and a propensity for transformation to acute myeloid leukemia (AML). A wide spectrum of genetic aberrations has been associat...

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Detalhes bibliográficos
Main Authors: Slape, Christopher, Lin, Ying Wei, Hartung, Helge, Zhang, Zhenhua, Wolff, Linda, Aplan, Peter D
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518060/
https://ncbi.nlm.nih.gov/pubmed/18648006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jncimonographs/lgn014
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