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Retroviral insertional mutagenesis identifies genes that collaborate with NUP98‐HOXD13 during leukemic transformation

The t(2;11)(q31;p15) chromosomal translocation results in a fusion between the NUP98 and HOXD13genes and has been observed in patients with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML). We previously demonstrated that expression of the NUP98‐HOXD13 (NHD13) fusion gene in transgenic...

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Autori principali: Slape, Christopher, Hartung, Helge, Lin, Ying‐Wei, Bies, Juraj, Wolff, Linda, Aplan, Peter D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950322/
https://ncbi.nlm.nih.gov/pubmed/17545593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-0075
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