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A Pegylated Leptin Antagonist Ameliorates CKD-Associated Cachexia in Mice
Elevated serum leptin levels correlate with inflammation and predict changes in lean body mass in patients with CKD, and activation of the melanocortin system by leptin signaling mediates the pathophysiology of CKD-associated cachexia. We tested whether treatment with a pegylated leptin receptor ant...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Nephrology
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3871780/ https://ncbi.nlm.nih.gov/pubmed/24115476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013040432 |
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