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Pegylated Leptin Antagonist Is a Potent Orexigenic Agent: Preparation and Mechanism of Activity
Leptin, a pleiotropic adipokine, is a central regulator of appetite and weight and a key immunomodulatory protein. Although inborn leptin deficiency causes weight gain, it is unclear whether induced leptin deficiency in adult wild-type animals would be orexigenic. Previous work with a potent competi...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2703547/ https://ncbi.nlm.nih.gov/pubmed/19342450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1706 |
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