A Pegylated Leptin Antagonist Ameliorates CKD-Associated Cachexia in Mice

Elevated serum leptin levels correlate with inflammation and predict changes in lean body mass in patients with CKD, and activation of the melanocortin system by leptin signaling mediates the pathophysiology of CKD-associated cachexia. We tested whether treatment with a pegylated leptin receptor ant...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Cheung, Wai W., Ding, Wei, Gunta, Sujana S., Gu, Yong, Tabakman, Rinat, Klapper, Leah N., Gertler, Arieh, Mak, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2014
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871780/
https://ncbi.nlm.nih.gov/pubmed/24115476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013040432
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados