Human CD4+CD25+ Regulatory T Cells Are Sensitive to Low Dose Cyclophosphamide: Implications for the Immune Response

Regulatory T cells (Treg) play a pivotal role in the immune system since they inhibit the T cell response. It is well known that cyclophosphamide applied at low dose is able to stimulate the immune response while high dose cyclophosphamide exerts inhibitory activity. Data obtained in mice indicate t...

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Hlavní autoři: Heylmann, Daniel, Bauer, Martina, Becker, Huong, van Gool, Stefaan, Bacher, Nicole, Steinbrink, Kerstin, Kaina, Bernd
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871695/
https://ncbi.nlm.nih.gov/pubmed/24376696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083384
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