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Human CD4+CD25+ Regulatory T Cells Are Sensitive to Low Dose Cyclophosphamide: Implications for the Immune Response

Regulatory T cells (Treg) play a pivotal role in the immune system since they inhibit the T cell response. It is well known that cyclophosphamide applied at low dose is able to stimulate the immune response while high dose cyclophosphamide exerts inhibitory activity. Data obtained in mice indicate t...

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Detalhes bibliográficos
Main Authors: Heylmann, Daniel, Bauer, Martina, Becker, Huong, van Gool, Stefaan, Bacher, Nicole, Steinbrink, Kerstin, Kaina, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871695/
https://ncbi.nlm.nih.gov/pubmed/24376696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083384
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