Inflammation Regulates TMPRSS6 Expression via STAT5

TMPRSS6 is a regulated gene, with a crucial role in the regulation of iron homeostasis by inhibiting hepcidin expression. The main regulator of iron homeostasis, the antimicrobial peptide hepcidin, which also has a role in immunity, is directly upregulated by inflammation. In this study, we analyzed...

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Detalhes bibliográficos
Main Authors: Meynard, Delphine, Sun, Chia Chi, Wu, Qifang, Chen, Wenjie, Chen, Shanzhuo, Nelson, Caroline N., Waters, Michael J., Babitt, Jodie L., Lin, Herbert Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871639/
https://ncbi.nlm.nih.gov/pubmed/24376517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0082127
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