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The role of TMPRSS6/matriptase-2 in iron regulation and anemia

Matriptase-2, encoded by the TMPRSS6 gene, is a member of the type II transmembrane serine protease family. Matriptase-2 has structural and enzymatic similarities to matriptase-1, which has been implicated in cancer progression. Matriptase-2 was later established to be essential in iron homeostasis...

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Autors principals: Wang, Chia-Yu, Meynard, Delphine, Lin, Herbert Y.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053654/
https://ncbi.nlm.nih.gov/pubmed/24966834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00114
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