Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation

The cytokines RANKL and TNF activate NF-κB signaling in osteoclast precursors (OCPs) to induce osteoclast (OC) formation. Conversely, TNF can limit OC formation through NF-κB p100, which acts as an inhibitor, and TNF receptor–associated receptor 3 (TRAF3); however, a role for TRAF3 in RANKL-mediated...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Xiu, Yan, Xu, Hao, Zhao, Chen, Li, Jinbo, Morita, Yoshikazu, Yao, Zhenqiang, Xing, Lianping, Boyce, Brendan F.
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2013
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871219/
https://ncbi.nlm.nih.gov/pubmed/24316970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66947
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍