Loading...

RANKL cytokine enhances TNF-induced osteoclastogenesis independently of TNF receptor associated factor (TRAF) 6 by degrading TRAF3 in osteoclast precursors

Cytokines, including receptor activator of nuclear factor κB ligand (RANKL) and TNF, induce increased osteoclast (OC) formation and bone loss in postmenopausal osteoporosis and inflammatory arthritides. RANKL and TNF can independently induce OC formation in vitro from WT OC precursors via TNF recept...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Yao, Zhenqiang, Lei, Wei, Duan, Rong, Li, Yanyun, Luo, Lu, Boyce, Brendan F.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5473222/
https://ncbi.nlm.nih.gov/pubmed/28438834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.771816
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!