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Coevolutionary signals across protein lineages help capture multiple protein conformations
A long-standing problem in molecular biology is the determination of a complete functional conformational landscape of proteins. This includes not only proteins’ native structures, but also all their respective functional states, including functionally important intermediates. Here, we reveal a sign...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870752/ https://ncbi.nlm.nih.gov/pubmed/24297889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315625110 |
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