Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells

We examined the gene expression and DNA methylation of 49 human induced pluripotent stem cells (hiPSCs) and 10 human embryonic stem cells and found overlapped variations in gene expression and DNA methylation in the two types of human pluripotent stem cell lines. Comparisons of the in vitro neural d...

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Auteurs principaux: Koyanagi-Aoi, Michiyo, Ohnuki, Mari, Takahashi, Kazutoshi, Okita, Keisuke, Noma, Hisashi, Sawamura, Yuka, Teramoto, Ito, Narita, Megumi, Sato, Yoshiko, Ichisaka, Tomoko, Amano, Naoki, Watanabe, Akira, Morizane, Asuka, Yamada, Yasuhiro, Sato, Tosiya, Takahashi, Jun, Yamanaka, Shinya
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870695/
https://ncbi.nlm.nih.gov/pubmed/24259714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319061110
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