Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells

We examined the gene expression and DNA methylation of 49 human induced pluripotent stem cells (hiPSCs) and 10 human embryonic stem cells and found overlapped variations in gene expression and DNA methylation in the two types of human pluripotent stem cell lines. Comparisons of the in vitro neural d...

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Main Authors: Koyanagi-Aoi, Michiyo, Ohnuki, Mari, Takahashi, Kazutoshi, Okita, Keisuke, Noma, Hisashi, Sawamura, Yuka, Teramoto, Ito, Narita, Megumi, Sato, Yoshiko, Ichisaka, Tomoko, Amano, Naoki, Watanabe, Akira, Morizane, Asuka, Yamada, Yasuhiro, Sato, Tosiya, Takahashi, Jun, Yamanaka, Shinya
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2013
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870695/
https://ncbi.nlm.nih.gov/pubmed/24259714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319061110
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