Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells

We examined the gene expression and DNA methylation of 49 human induced pluripotent stem cells (hiPSCs) and 10 human embryonic stem cells and found overlapped variations in gene expression and DNA methylation in the two types of human pluripotent stem cell lines. Comparisons of the in vitro neural d...

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Autori principali: Koyanagi-Aoi, Michiyo, Ohnuki, Mari, Takahashi, Kazutoshi, Okita, Keisuke, Noma, Hisashi, Sawamura, Yuka, Teramoto, Ito, Narita, Megumi, Sato, Yoshiko, Ichisaka, Tomoko, Amano, Naoki, Watanabe, Akira, Morizane, Asuka, Yamada, Yasuhiro, Sato, Tosiya, Takahashi, Jun, Yamanaka, Shinya
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3870695/
https://ncbi.nlm.nih.gov/pubmed/24259714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319061110
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