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Free energy landscapes for initiation and branching of protein aggregation
Experiments on artificial multidomain protein constructs have probed the early stages of aggregation processes, but structural details of the species that initiate aggregation remain elusive. Using the associative-memory, water-mediated, structure and energy model known as AWSEM, a transferable coar...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3870682/ https://ncbi.nlm.nih.gov/pubmed/24284165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320483110 |
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