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The Aggregation Free Energy Landscapes of Polyglutamine Repeats
Aggregates of proteins containing polyglutamine (polyQ) repeats are strongly associated with several neurodegenerative diseases. The length of the repeats correlates with the severity of the disease. Previous studies have shown that pure polyQ peptides aggregate by nucleated growth polymerization an...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5803750/ https://ncbi.nlm.nih.gov/pubmed/27786478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b08665 |
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