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The Aggregation Free Energy Landscapes of Polyglutamine Repeats
Aggregates of proteins containing polyglutamine (polyQ) repeats are strongly associated with several neurodegenerative diseases. The length of the repeats correlates with the severity of the disease. Previous studies have shown that pure polyQ peptides aggregate by nucleated growth polymerization an...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5803750/ https://ncbi.nlm.nih.gov/pubmed/27786478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b08665 |
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