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Energy landscapes of a mechanical prion and their implications for the molecular mechanism of long-term memory

Aplysia cytoplasmic polyadenylation element binding (CPEB) protein, a translational regulator that recruits mRNAs and facilitates translation, has been shown to be a key component in the formation of long-term memory. Experimental data show that CPEB exists in at least a low-molecular weight coiled-...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Chen, Mingchen, Zheng, Weihua, Wolynes, Peter G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983853/
https://ncbi.nlm.nih.gov/pubmed/27091989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602702113
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