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Expression of DNA Translesion Synthesis Polymerase η in Head and Neck Squamous Cell Cancer Predicts Resistance to Gemcitabine and Cisplatin-Based Chemotherapy

PURPOSE: The development of resistance against anticancer drugs has been a persistent clinical problem for the treatment of locally advanced malignancies in the head and neck mucosal derived squamous cell carcinoma (HNSCC). Recent evidence indicates that the DNA translesion synthesis (TLS) polymeras...

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Bibliografski detalji
Glavni autori: Zhou, Wendi, Chen, Yih-wen, Liu, Xiyong, Chu, Peiguo, Loria, Sofia, Wang, Yafan, Yen, Yun, Chou, Kai-Ming
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869838/
https://ncbi.nlm.nih.gov/pubmed/24376779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083978
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