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Expression of DNA Translesion Synthesis Polymerase η in Head and Neck Squamous Cell Cancer Predicts Resistance to Gemcitabine and Cisplatin-Based Chemotherapy

PURPOSE: The development of resistance against anticancer drugs has been a persistent clinical problem for the treatment of locally advanced malignancies in the head and neck mucosal derived squamous cell carcinoma (HNSCC). Recent evidence indicates that the DNA translesion synthesis (TLS) polymeras...

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Detalhes bibliográficos
Main Authors: Zhou, Wendi, Chen, Yih-wen, Liu, Xiyong, Chu, Peiguo, Loria, Sofia, Wang, Yafan, Yen, Yun, Chou, Kai-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869838/
https://ncbi.nlm.nih.gov/pubmed/24376779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083978
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