Expression of DNA Translesion Synthesis Polymerase η in Head and Neck Squamous Cell Cancer Predicts Resistance to Gemcitabine and Cisplatin-Based Chemotherapy

PURPOSE: The development of resistance against anticancer drugs has been a persistent clinical problem for the treatment of locally advanced malignancies in the head and neck mucosal derived squamous cell carcinoma (HNSCC). Recent evidence indicates that the DNA translesion synthesis (TLS) polymeras...

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Main Authors: Zhou, Wendi, Chen, Yih-wen, Liu, Xiyong, Chu, Peiguo, Loria, Sofia, Wang, Yafan, Yen, Yun, Chou, Kai-Ming
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869838/
https://ncbi.nlm.nih.gov/pubmed/24376779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0083978
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