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Differential analysis of gene regulation at transcript resolution with RNA-seq

Differential analysis of gene and transcript expression using high-throughput RNA sequencing (RNA-seq) is complicated by several sources of measurement variability and poses numerous statistical challenges. We present Cuffdiff 2, an algorithm that estimates expression at transcript-level resolution...

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Autori principali: Trapnell, Cole, Hendrickson, David G, Sauvageau, Martin, Goff, Loyal, Rinn, John L, Pachter, Lior
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869392/
https://ncbi.nlm.nih.gov/pubmed/23222703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.2450
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