Chargement en cours...
Improving RNA-Seq expression estimates by correcting for fragment bias
The biochemistry of RNA-Seq library preparation results in cDNA fragments that are not uniformly distributed within the transcripts they represent. This non-uniformity must be accounted for when estimating expression levels, and we show how to perform the needed corrections using a likelihood based...
Enregistré dans:
| Auteurs principaux: | , , , , |
|---|---|
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2011
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129672/ https://ncbi.nlm.nih.gov/pubmed/21410973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-3-r22 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|