Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

Recent advances in high-throughput cDNA sequencing (RNA-seq) can reveal new genes and splice variants and quantify expression genome-wide in a single assay. The volume and complexity of data from RNA-seq experiments necessitate scalable, fast and mathematically principled analysis software. TopHat a...

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Bibliografiska uppgifter
Huvudupphovsmän: Trapnell, Cole, Roberts, Adam, Goff, Loyal, Pertea, Geo, Kim, Daehwan, Kelley, David R, Pimentel, Harold, Salzberg, Steven L, Rinn, John L, Pachter, Lior
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334321/
https://ncbi.nlm.nih.gov/pubmed/22383036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.016
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