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Gene-level differential analysis at transcript-level resolution
Compared to RNA-sequencing transcript differential analysis, gene-level differential expression analysis is more robust and experimentally actionable. However, the use of gene counts for statistical analysis can mask transcript-level dynamics. We demonstrate that ‘analysis first, aggregation second,...
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| Publicado en: | Genome Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5896116/ https://ncbi.nlm.nih.gov/pubmed/29650040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1419-z |
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