Minimally invasive transplantation of iPSC-derived ALDHhiSSCloVLA4+ neural stem cells effectively improves the phenotype of an amyotrophic lateral sclerosis model

Amyotrophic lateral sclerosis (ALS) is a fatal neurological disease characterized by the degeneration of motor neurons. Currently, there is no effective therapy for ALS. Stem cell transplantation is a potential therapeutic strategy for ALS, and the reprogramming of adult somatic cells into induced p...

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Détails bibliographiques
Auteurs principaux: Nizzardo, Monica, Simone, Chiara, Rizzo, Federica, Ruggieri, Margherita, Salani, Sabrina, Riboldi, Giulietta, Faravelli, Irene, Zanetta, Chiara, Bresolin, Nereo, Comi, Giacomo P., Corti, Stefania
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869354/
https://ncbi.nlm.nih.gov/pubmed/24006477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt425
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