Development of a Stable Virus-Like Particle Vaccine Formulation against Chikungunya Virus and Investigation of the Effects of Polyanions

Chikungunya virus (CHIKV) is an alphavirus that infects millions of people every year, especially in the developing world. The selective expression of recombinant CHIKV capsid and envelope proteins results in the formation of self-assembled virus-like particles (VLPs) that have been shown to protect...

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Main Authors: Kramer, Ryan M., Zeng, Yuhong, Sahni, Neha, Kueltzo, Lisa A., Schwartz, Richard M., Srivastava, Indresh K., Crane, Lindsey, Joshi, Sangeeta B., Volkin, David B., Middaugh, C. Russell
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3869236/
https://ncbi.nlm.nih.gov/pubmed/24129946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23749
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