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Transplant Tolerance to Pancreatic Islets Is Initiated in the Graft and Sustained in the Spleen

The immune system is comprised of several CD4(+) T regulatory (Treg) cell types, of which two, the Foxp3(+) Treg and T regulatory type 1 (Tr1) cells, have frequently been associated with transplant tolerance. However, whether and how these two Treg-cell types synergize to promote allograft tolerance...

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Bibliografiska uppgifter
Huvudupphovsmän:	Gagliani, N., Jofra, T., Valle, A., Stabilini, A., Morsiani, C., Gregori, S., Deng, S., Rothstein, D. M., Atkinson, M., Kamanaka, M., Flavell, R. A., Roncarolo, M. G., Battaglia, M.
Materialtyp:	Artigo
Språk:	Inglês
Publicerad:	2013
Ämnen:	Article
Länkar:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3869180/ https://ncbi.nlm.nih.gov/pubmed/23834659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12333
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Transplant Tolerance to Pancreatic Islets Is Initiated in the Graft and Sustained in the Spleen

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