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Transplant Tolerance to Pancreatic Islets Is Initiated in the Graft and Sustained in the Spleen
The immune system is comprised of several CD4(+) T regulatory (Treg) cell types, of which two, the Foxp3(+) Treg and T regulatory type 1 (Tr1) cells, have frequently been associated with transplant tolerance. However, whether and how these two Treg-cell types synergize to promote allograft tolerance...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3869180/ https://ncbi.nlm.nih.gov/pubmed/23834659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.12333 |
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