Rapamycin Combined with Anti-CD45RB mAb and IL-10 or with G-CSF Induces Tolerance in a Stringent Mouse Model of Islet Transplantation

BACKGROUND: A large pool of preexisting alloreactive effector T cells can cause allogeneic graft rejection following transplantation. However, it is possible to induce transplant tolerance by altering the balance between effector and regulatory T (Treg) cells. Among the various Treg-cell types, Foxp...

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Hlavní autoři: Gagliani, Nicola, Gregori, Silvia, Jofra, Tatiana, Valle, Andrea, Stabilini, Angela, Rothstein, David M., Atkinson, Mark, Roncarolo, Maria Grazia, Battaglia, Manuela
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235119/
https://ncbi.nlm.nih.gov/pubmed/22174806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028434
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