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Antigen-Specific Dependence of Tr1-Cell Therapy in Preclinical Models of Islet Transplant
OBJECTIVE: In type 1 diabetes, allogeneic pancreatic islet transplant restores insulin production, but life-threatening immunosuppression is required to avoid graft rejection. Induction of antigen (Ag)–specific tolerance by cell therapy with regulatory T-cells (Tregs) represents an attractive altern...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Diabetes Association
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2809952/ https://ncbi.nlm.nih.gov/pubmed/19934002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1168 |
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