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A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes
The adaptor protein TRAF3 restrains B cell activating factor receptor (BAFFR) and CD40-mediated activation of the NF-κB2 pathway in B cells. Mice lacking TRAF3 specifically in B cells revealed the critical role of TRAF3 in restraining homeostatic B cell survival. Furthermore, loss-of-function mutati...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3868921/ https://ncbi.nlm.nih.gov/pubmed/24391649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00477 |
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