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TRAF3 Controls Activation of the Canonical and Alternative NFκB by the Lymphotoxin Beta Receptor

Components of lymphotoxin beta receptor (LTBR)-associated signaling complexes, including TRAF2, TRAF3, NIK, IKK1, and IKK2 have been shown to participate in the coupling of LTBR to NFκB. Here, we report that TRAF3 functions as a negative regulator of LTBR signaling via both canonical and non-canonic...

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Autors principals: Bista, Pradeep, Zeng, Weike, Ryan, Sarah, Bailly, Veronique, Browning, Jeffrey L., Lukashev, Matvey E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857099/
https://ncbi.nlm.nih.gov/pubmed/20185819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.076091
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