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Inhibiting TRAF2-mediated Activation of NF-κB Facilitates Induction of AP-1
The compound 5-(4-methoxyarylimino)-2-N-(3,4-dichlorophenyl)-3-oxo-1,2,4-thiadiazolidine (P(3)-25) is known to possess anti-bacterial, anti-fungal, and anti-tubercular activities. In this report, we provide evidence that P(3)-25 inhibits NF-κB, known to induce inflammatory and tumorigenic responses....
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857039/ https://ncbi.nlm.nih.gov/pubmed/20133937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094961 |
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