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Azadirachtin Interacts with Retinoic Acid Receptors and Inhibits Retinoic Acid-mediated Biological Responses

Considering the role of retinoids in regulation of more than 500 genes involved in cell cycle and growth arrest, a detailed understanding of the mechanism and its regulation is useful for therapy. The extract of the medicinal plant Neem (Azadirachta indica) is used against several ailments especiall...

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Autors principals: Thoh, Maikho, Babajan, Banaganapalli, Raghavendra, Pongali B., Sureshkumar, Chitta, Manna, Sunil K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3039373/
https://ncbi.nlm.nih.gov/pubmed/21127062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.169334
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