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The Role of TRAF2 Binding to the Type I Interferon Receptor in Alternative NFκB Activation and Antiviral Response

Type I interferons (IFNs) play critical roles in the host defense by modulating gene expression through the IFN-dependent activation of STAT and NFκB transcription factors. Previous studies established that IFN activates NFκB through a classical NFκB pathway that results in IκBα degradation and form...

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Autori principali: Yang, Chuan He, Murti, Aruna, Pfeffer, Susan R., Fan, Meiyun, Du, Ziyun, Pfeffer, Lawrence M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2386940/
https://ncbi.nlm.nih.gov/pubmed/18362156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M708895200
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