Viral Induction of the Zinc Finger Antiviral Protein Is IRF3-dependent but NF-κB-independent

The zinc finger antiviral protein (ZAP) is an interferon-stimulated gene that restricts the replication of retroviruses, alphaviruses, and filoviruses. Relatively little is known, however, regarding the detailed mechanism of ZAP induction during viral infections. We show that, although being inducib...

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Detalhes bibliográficos
Main Authors: Wang, Nan, Dong, Qingming, Li, Jingjing, Jangra, Rohit K., Fan, Meiyun, Brasier, Allan R., Lemon, Stanley M., Pfeffer, Lawrence M., Li, Kui
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825402/
https://ncbi.nlm.nih.gov/pubmed/20048147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.054486
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