Viral Induction of the Zinc Finger Antiviral Protein Is IRF3-dependent but NF-κB-independent

The zinc finger antiviral protein (ZAP) is an interferon-stimulated gene that restricts the replication of retroviruses, alphaviruses, and filoviruses. Relatively little is known, however, regarding the detailed mechanism of ZAP induction during viral infections. We show that, although being inducib...

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Hlavní autoři: Wang, Nan, Dong, Qingming, Li, Jingjing, Jangra, Rohit K., Fan, Meiyun, Brasier, Allan R., Lemon, Stanley M., Pfeffer, Lawrence M., Li, Kui
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2825402/
https://ncbi.nlm.nih.gov/pubmed/20048147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.054486
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