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An Atypical E3 Ligase Zinc Finger Protein 91 Stabilizes and Activates NF-κB-inducing Kinase via Lys(63)-linked Ubiquitination

The NF-κB transcription factors control many physiological processes, including inflammation, immunity, and apoptosis. Its activity contributes to the development of various cell malignancies. NF-κB-inducing kinase (NIK) plays a pivotal role in NF-κB activation. However, the molecular mechanism to s...

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Detalhes bibliográficos
Main Authors: Jin, Xuejun, Jin, Hong Ri, Jung, Haeng Sun, Lee, Se Jeong, Lee, Jeong-Hyung, Lee, Jung Joon
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945548/
https://ncbi.nlm.nih.gov/pubmed/20682767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.129551
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