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Mutagenesis analysis of the zinc-finger antiviral protein

BACKGROUND: The zinc-finger antiviral protein (ZAP) specifically inhibits the replication of certain viruses, including murine leukemia virus (MLV), by preventing the accumulation of viral mRNA in the cytoplasm. ZAP directly binds to the viral mRNA through the zinc-finger motifs and recruits the RNA...

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Autores principales: Wang, Xinlu, Lv, Fengxiang, Gao, Guangxia
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847535/
https://ncbi.nlm.nih.gov/pubmed/20226086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-19
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