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Mutagenesis analysis of the zinc-finger antiviral protein

BACKGROUND: The zinc-finger antiviral protein (ZAP) specifically inhibits the replication of certain viruses, including murine leukemia virus (MLV), by preventing the accumulation of viral mRNA in the cytoplasm. ZAP directly binds to the viral mRNA through the zinc-finger motifs and recruits the RNA...

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Bibliographic Details
Main Authors: Wang, Xinlu, Lv, Fengxiang, Gao, Guangxia
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847535/
https://ncbi.nlm.nih.gov/pubmed/20226086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-19
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