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Glycogen Synthase Kinase 3β (GSK3β) Modulates Antiviral Activity of Zinc-finger Antiviral Protein (ZAP)

Zinc-finger antiviral protein (ZAP) is a host factor that specifically inhibits the replication of certain viruses, including HIV-1, Ebola virus, and Sindbis virus. ZAP binds directly to specific viral mRNAs and recruits cellular mRNA degradation machinery to degrade the target RNA. ZAP has also bee...

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Autors principals: Sun, Lin, Lv, Fengxiang, Guo, Xuemin, Gao, Guangxia
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3391094/
https://ncbi.nlm.nih.gov/pubmed/22514281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.306373
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