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p72 DEAD box RNA helicase is required for optimal function of the zinc-finger antiviral protein

The zinc-finger antiviral protein (ZAP) specifically inhibits the replication of many viruses by preventing the accumulation of viral mRNAs in the cytoplasm. ZAP directly binds to the viral mRNAs and recruits the RNA exosome to degrade the target RNA. In the present study, we identified the p72 DEAD...

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Detalhes bibliográficos
Main Authors: Chen, Guifang, Guo, Xuemin, Lv, Fengxiang, Xu, Yihui, Gao, Guangxia
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393818/
https://ncbi.nlm.nih.gov/pubmed/18334637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712276105
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