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Unphosphorylated STAT3 regulates the antiproliferative, antiviral, and gene-inducing actions of Type I interferons

Type I interferon (IFNα/β) induces antiviral and antiproliferative responses in cells through the induction of IFN-stimulated genes (ISGs). Although the roles of IFN-activated STAT1 and STAT2 in the IFN response are well described, the function of STAT3 is poorly characterized. We investigated the r...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Pfeffer, Susan R., Fan, Meiyun, Du, Ziyun, Yang, Chuan He, Pfeffer, Lawrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5546317/
https://ncbi.nlm.nih.gov/pubmed/28642132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.06.111
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