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TRAF3 as a Multifaceted Regulator of B Lymphocyte Survival and Activation

The adaptor protein TNF receptor-associated factor 3 (TRAF3) serves as a powerful negative regulator in multiple aspects of B cell biology. Early in vitro studies in transformed cell lines suggested the potential of TRAF3 to inhibit signaling by its first identified binding receptor, CD40. However,...

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Pubblicato in:Front Immunol
Autori principali: Bishop, Gail A., Stunz, Laura L., Hostager, Bruce S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165887/
https://ncbi.nlm.nih.gov/pubmed/30319624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02161
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