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Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene.

The synthesis of cytochrome P-450c is induced remarkably in cultured cells as well as animal tissues in response to added chemicals such as 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzodioxin. To study this mechanism, we joined the sequence of 5'-flanking and upstream regions of the P-450c gen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Sogawa, K, Fujisawa-Sehara, A, Yamane, M, Fujii-Kuriyama, Y
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386863/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3464941/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.21.8044
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