Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene.
The synthesis of cytochrome P-450c is induced remarkably in cultured cells as well as animal tissues in response to added chemicals such as 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzodioxin. To study this mechanism, we joined the sequence of 5'-flanking and upstream regions of the P-450c gen...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1986
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC386863/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3464941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.83.21.8044 |
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