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Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene.

The synthesis of cytochrome P-450c is induced remarkably in cultured cells as well as animal tissues in response to added chemicals such as 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzodioxin. To study this mechanism, we joined the sequence of 5'-flanking and upstream regions of the P-450...

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Bibliografske podrobnosti
Main Authors: Sogawa, K, Fujisawa-Sehara, A, Yamane, M, Fujii-Kuriyama, Y
Format: Artigo
Jezik:Inglês
Izdano: 1986
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC386863/
https://ncbi.nlm.nih.gov/pubmed/3464941
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